In Vitro Study of Kaempferia galanga L. Compound, δ- 3-Carene, Against 5-Lipoxygenase

Supandi Supandi, Supandi

Kaempferia galanga has anti-inflammatory activity and worth developing as lipoxygenase inhibitors. The aim of this study was to determined δ-3-carene, one of the potential compounds of K. galanga, as a lipoxygenase inhibitor. The LOX-inhibitor activity was tested in-vitro. The result showed that the IC50 of δ-3-carene was 23.10 μM, which was less potential compare to zileuton (7.54 μM). The study showed that K. galanga contains possible active components that could be developed as 5-LOX-inhibitor.

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